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Professor Doreen Cantrell - Public Lecture Award 2020-2021

Professor Doreen Cantrell from University of Dundee was presented with the 2020 ISI Public Lecture Award by ISI President, Prof. Annie Curtis. Due to COVID-19 restrictions the 2020 award was presented in absentia in 2021.



Prof Doreen Cantrell, Cell Signalling and Immunology, School of Life Sciences - University of Dundee


Biography

Prof Doreen Cantrell

Professor of Cellular Immunology at the School of Life Sciences, University of Dundee.


Doreen Cantrell CBE, FRS, FRSE, FMedSci, is a renowned immunologist at the School of Life Sciences, University of Dundee. Her research focuses on the development and activation of T lymphocytes, which play a crucial role in understanding the immune response.


Her laboratory's main interest is studying the signal transduction pathways that control T lymphocyte metabolism, migration, and differentiation to define the contribution of specific biochemical pathways to T cell activation and understand how T cells make appropriate responses to control T cell development and peripheral T cell function.

Her lab has made significant progress in mapping serine/threonine kinase-mediated signalling pathways in thymocytes and peripheral T cells. Dr Cantrell's work has been instrumental to identifying essential regulators of T cell metabolism, the effector cytotoxic T cell effector function, and CD8 T cell migration/trafficking. Her lab's work aims to generate a molecular understanding of how signal transduction pathways control T cell function, providing new insights into pharmacological strategies that could manipulate immune responses to ensure effective vaccination or restrain T cell pathology caused by effector T cells.

Prof Cantrell has published over 150 research papers many in top-tier, high-impact journals, including Nature and Science. She has supervised nearly 100 PhD students and post-doctoral researchers and has been the recipient of several awards including being elected a Fellow of the Academy of Medical Sciences and of EMBO in 2000, Fellow of the Royal Society of Edinburgh in 2005 and as a Fellow of the Royal Society in 2011 and she has also been appointed "Commander of the Order of the British Empire (CBE) in the 2014 New Year Honours for services to life sciences". She has served and continue to serve in various scientific committees and editorial boards and is a council member of the Medical Research Council and sits on the Sir Henry Dale Early Career Fellowships panel.


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