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Research Assistant position at the TB Immunology Research Group, TCD

Applications are invited from candidates for a full time Research Assistant post funded by the Royal City of Dublin Hospital Trust (RCDH) at the TB Immunology Research Group, TTMI, Trinity College Dublin.

Description: Post Summary Tuberculosis (TB) remains a global challenge causing more than one million deaths annually. TB therapy is characterised by a long duration of treatment and the administration of several antibiotic drugs to overcome drug resistance. The increasing prevalence of drug-resistant TB demonstrates that current treatments are inadequate and there is an urgent need for novel therapies. Research is now focused on the development of host-directed therapies which can be used in combination with existing antimicrobials, with a special focus on promoting host defense, particularly cellular metabolism. The current post focuses on the use of new and 2 innovative strategies, aimed at boosting the host response, increasing antibiotic efficacy and decreasing our reliance on antibiotics in the clinic. Further details of Prof. Joe Keane’s research group can be found at The appointee will work as part of a team of post-doctoral scientists and graduate students led by Professor Keane. The tuberculosis immunology research group uses primary human cells and molecular biology techniques to study macrophage, neutrophil, dendritic cell and T cell responses to Mycobacterium tuberculosis infection. Techniques that will be employed by the successful candidate include cell culture, ELISA, RT-qPCR, cell migration assays, flow cytometry and Seahorse metabolic flux assays.

Application: Applicants should send a single PDF consisting of a cover letter outlining their suitability for the post, their CV and the names and contact details of 2 referees by email to Dr Donal Cox

Please insert ‘Research Assistant Position 2022’ in the subject line of the email.

Deadline: 12 pm Friday 18th November 2022 (Irish Standard Time)

More details on the role can be found in the document below:

Research Assistant TB Immunology
Download PDF • 267KB


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