2017 – Meeting Programme



    14th and 15th September 2017

    Tercentenary Hall,

    Trinity Biomedical Sciences Institute, Trinity College, Dublin 2


    Thursday, 14th September 2017
    08:00 – 08:50 Conference Registration
    08:50 – 09:00 Conference Open/Welcome: Prof. Ed Lavelle, Trinity College Dublin
    President, Irish Society for Immunology
    Chair: Dr. Beth Brint, University College Cork
    09:00 – 09:40 Molecular mechanisms underlying the cellular decision to respond to inflammatory stimuli
    Dr. Ruaidhri Carmody
    University of Glasgow, U.K.
    09:40 – 10:20 Disruption of macrophage/microglial metabolism in a model of Alzheimer’s disease
    Prof. Marina Lynch
    Trinity College Dublin, Ireland
    10:20 – 11:00 Tea/Coffee, Posters and Trade Exhibitions
    11:00 – 11:15 S01: A SNP in time: The effect of MALD96N in TLR signallingJennifer Dowling
    Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, Clayton, Victoria, Australia
    11:15 – 11:30 S02: Molluscum Contagiosum Virus protein MC005 inhibits innate virus sensing and pro-inflammatory cytokine-mediated activation of the IKK complex and NFκB by targeting IKKγ/NEMO
    Gareth Brady
    Trinity College Dublin, Ireland
    11:30 – 11:45 S03: Modulation of membrane fluidity regulates IL-10 production by dendritic cells
    Sean McCluskey
    Trinity College Dublin, Ireland
    11:45 – 12:00 S04: IL-36 cytokines alter the composition of the intestinal microbiome to protect against obesity and metabolic dysfunction
    Eirini Giannoudaki
    National Children’s Research Centre, Our Lady’s Children’s Hospital and Trinity College Dublin, Ireland
    12:00 – 12:50 Selected 3 min Flash Presentations Session I
    Chair: Dr. Derek Doherty
    Trinity College Dublin
    12:50 – 13:45 Lunch, Posters and Trade Exhibitions
    Chair: Prof. Padraic Fallon, Trinity College Dublin
    13:45 – 14:25 Regulation of epithelial barrier in allergic diseases
    Prof. Cezmi Akdis
    Swiss Institute of Allergy and Asthma Research, Davos, Switzerland
    14:25 – 15:05 Molecular re-classification of immune mediated diseases – a focus on systemic sclerosis
    Prof. Dr. Timothy Radstake
    UMC Utrecht, The Netherlands
    15:05 – 15:20 S05: Tumour Infiltrating monocytes correlate with CD8+ T cells in a subset of colorectal cancer (CRC) tumours with high CCL3 and CCL5 expression and intact aerobic respiration.
    Louise Elliott
    St.Vincent’s University Hospital, Dublin, Ireland
    15:20 – 15:35 S06: Investigating the role of IL-6 on macrophage phenotypes in fibrotic disease
    Emma Doran
    Genentech Inc., South San Francisco, California, USA.
    15:35 – 15:50 S07: Distinct pathogenic mechanisms and transcriptomic signatures of joint specific CD141+ dendritic cells
    Mary Canavan
    Trinity College Dublin, Ireland
    15:50 – 16:15 Tea/Coffee, Posters and Trade Exhibitions
    16:15 – 16:55 Skin: immunity, reaction and vaccination
    Dr. Bénazine Combadiere
    INSERM, Paris, France
    17:00 – 19:00 Posters, Wine Reception and Trade Exhibitions
    19:00 – 23:00
    Banquet Dinner – Ely Brasserie
    Friday, 15th September 2017
    Chair: Dr. Denise Fitzgerald, Queen’s University, Belfast
    09:00 – 09:40 Circadian rhythms in adaptive and innate immunity
    Dr. Christoph Scheiermann
    Ludwig-Maximilians Universitat University, Munich, Germany
    09:40 – 10:20 T cells and TB –friends or foes?
    Prof. Andrea Cooper
    University of Leicester, U.K.
    10:20 – 10:45 Tea/Coffee, Posters and Trade Exhibitions
    10:45 – 11:25 Death receptors, inflammation and cancer
    Prof. Seamus Martin
    Trinity College Dublin, Ireland
    11:25 – 11:40 S08: Prostaglandin E2 protects against caspase-11 – induced cell death.
    Zbigniew Zaslona
    Trinity College Dublin, Ireland
    11:40 – 11:55 S09: Obesity induces metabolic reprogramming in natural killer cells leading to defects in cancer immune surveillance
    Lydia Dyck
    Trinity College Dublin, Ireland and Harvard Medical School
    11:55 – 12:10 S10: TLR2 bridges oxidative stress and complement activation in a model of Age-related macular degeneration (AMD)
    Kelly Mulfaul
    The National Children’s Research Centre, Our Lady’s Children’s Hospital, Dublin, Ireland
    12:10 – 13:00 Selected 3 min Flash Presentations Session II
    Chair: Dr. Annie Curtis
    Royal College of Surgeons in Ireland
    13:00 – 14:00 Lunch, Posters and Trade Exhibitions
    Chair: Prof. Paul Moynagh, Maynooth University
    14:00 – 14:40 Islet inflammation in type 2 diabetes: from physiology to therapy
    Prof. Mark Donath
    University of Basel, Switzerland
    14:40 – 14:55 S11: Interleukin-17 receptor A regulates cutaneous immunity to maintain the integrity of the skin barrier to prevent allergic skin inflammation
    Achilleas Floudas
    Trinity College Dublin, Ireland
    14:55 – 15:10 S12: Arginase-2 is essential for mitochondria-associated functions in M2-polarised macrophages.
    Claire McCoy
    Hudson Institute of Medical Research, Monash University, Australia and Royal College of Surgeons in Ireland
    15:10– 15:25 S13: NOD1 and NOD2 activation prevent autoimmune disease through innate immune training
    Mark Lynch
    Trinity College Dublin, Ireland
    15:25 – 15:50 Tea/Coffee, Posters and Trade Exhibitions
    15:50 – 16:30 Warburg meet macrophages: how metabolic reprogramming is providing new insights into immunoregulation and inflammation
    Prof. Luke O’Neill
    Trinity College Dublin, Ireland
    16:30 – 17:00 Award of Presentation Prizes
    Close of Conference