Prof. Angela Santoni
Prof. Santoni’s webpage
Research Interests: Over the last 20 years, the main interests of Prof.Santoni have been focused on understanding several aspects of NK cell biology. In particular she has been involved in studying the role of the intracellular signaling pathways triggered by several surface activation/adhesion receptors in NK cell functions, first demonstrating that integrins function as signaling receptors in NK cells. More recently she has been interested in analyzing the molecular mechanisms regulating the expression of NK cell activating receptor ligands on both normal and neoplastic cells. She has first proposed that NK cells may represent an immunosurveillance mechanism eliminating senescent cells.