Prof. Cezmi Akdis
Swiss Institute of Allergy and Asthma Research, Davos, Switzerland
Research Interests: Immunology / Cellular Allergy.
Substantial progress in understanding mechanisms of immune regulation in allergy, asthma, autoimmune diseases, tumors, organ transplantation and chronic infections has led to a variety of possibilities for targeted therapeutic approaches. In chronic allergic inflammation, immune system cells and thei cytokines interact with resident tissue cells, which leads to a series of tissue events after the activation, and proinflammatory cytokine and chemokine release from both sides. Some of these events seem to be part of the immune pathology, such as basement membrane thickening, epithelial death, desquamation and spongiosis, however, they also act as mechanisms that control the severity of tissue inflammation.